Desire Shot (Bremelanotide Injection)

About Vitamin E

FDA-approved in 2019 for hypoactive sexual desire disorder (HSDD) in premenopausal women, bremelanotide is the first and only on-demand injectable treatment for female desire.

It is:

• Non-hormonal

• Rapid-acting

• Safe for intermittent use

It works by awakening dormant neural pathways involved in sexual interest, helping women feel more naturally “in the mood” when intimacy arises.

Who Might Benefit

The Desire Shot may be helpful for women who:

• Struggle with low or absent sexual desire

• Feel disconnected from intimacy, even with a supportive partner

• Have a history of SSRI-related libido suppression

• Experience low motivation despite emotional closeness

• Want to feel more naturally interested in sex without using hormones

💡 Especially valuable for women who say, “I love my partner—I just don’t want sex.”

How to Use It

• Inject just under the skin of the abdomen or thigh ~45 minutes before anticipated intimacy

• Use only as needed (not more than once in 24 hours)

• Effects may last up to 6–12 hours

• Comes in a pre-measured vial with included syringes

• Store at room temperature; follow provider’s specific instructions

You’ll be guided on timing, technique, and frequency to best match your goals.

How It Works

Bremelanotide is a melanocortin receptor agonist that acts on the brain’s hypothalamus—an area responsible for regulating sexual desire. It stimulates neural pathways involved in motivation and reward, increasing sexual interest and responsiveness.

Unlike medications that target blood flow, bremelanotide works centrally, supporting emotional and psychological readiness for intimacy.

When to Expect Results

• Some women notice subtle desire or interest increase within 30–60 minutes

• Emotional connection and physical responsiveness may follow during intimacy

• Desire may feel more natural, not forced—without the need to “psych yourself up”

• Regular use before intimacy may help retrain desire pathways over time

When to Contact Your Provider

Let us know if you experience:

• Persistent nausea or headache

• Dizziness or palpitations

• No improvement after 3–4 uses

• Concerns about emotional response or overuse

We’ll help adjust your protocol or explore alternatives as needed.

Possible Side Effects

Most women tolerate the Desire Shot well. Possible effects may include:

• Nausea or mild flushing (most common)

• Headache or dizziness

• Temporary increase in blood pressure

• Rare: injection site irritation

Tip: Eating a small snack before the injection can reduce nausea risk.

🚫 Not for use in women with uncontrolled high blood pressure or known cardiovascular issues.

Frequently Asked Questions

Q: Will this make me feel aroused instantly?
A: Not like a stimulant—it supports natural desire by acting on the brain’s motivation centers. You may feel more open or interested, not “turned on” immediately.

Q: Is this safe for postmenopausal women?
A: While FDA-approved for premenopausal women, many providers use it off-label in postmenopausal women when appropriate.

Q: Can I combine it with hormone therapy or arousal cream?
A: Yes! It works well alongside topical estriol, testosterone, or oxytocin support.

Q: Do I have to inject it every time?
A: It’s on-demand, so only when you want the effects. Some women use it weekly; others reserve it for special moments or during intimacy rebuilding.

The Desire Shot is a prescription-only treatment. It is FDA-approved for HSDD in premenopausal women and may be used off-label in others based on your provider’s judgment. Always use under clinical supervision.

Medical Oversight Disclaimer

Optional Add-On Tools

Ask about combining your treatment with:

Arousal Creams

For enhanced touch sensitivity

Supplements

Adjunct to enhanse prescription treatments.

HIV prevention is for everyone who requires it. Women of all orientations are eligible.

PrEP

Contact Us

Reach out for inquiries about female arousal cream and sildenafil prescriptions. We're here to help!