Renew & Reclaim

About Renew & Reclaim

DHEA has been studied extensively for its role in reversing vaginal atrophy, especially in women who can’t or prefer not to use estrogen. It is FDA-approved in certain vaginal formulas (e.g., prasterone), and compounded DHEA creams offer customizable strengths and added moisturizers like vitamin E for enhanced comfort.

Who Might Benefit

Renew & Reclaim may be ideal for women who are:

• Experiencing vaginal dryness or discomfort

• Postmenopausal or perimenopausal

• Unable or unwilling to use estrogen therapy

• Recovering from birth control or hormonal suppression

• Experiencing pain with sex or decreased physical pleasure

• Managing vaginal thinning, irritation, or loss of tone

Particularly helpful for women with hormone-related vaginal atrophy or who are looking for non-estrogenic intimacy support.

How to Use It

• Apply a small amount vaginally once daily (or as directed)

• Use at bedtime for best absorption and comfort

• Can also be used 2–3 times weekly for maintenance

• Safe to combine with other intimacy or hormone treatments

Your provider will guide you on the correct frequency and amount based on your symptoms and goals.

How It Works

DHEA (dehydroepiandrosterone) is a hormone precursor naturally produced by the adrenal glands. When applied vaginally, it:

• Converts locally into small amounts of estrogen and testosterone

• Stimulates vaginal tissue repair and hydration

• Supports nerve sensitivity and blood flow

• Improves overall vaginal health and comfort

Because it acts locally, DHEA vaginal cream typically has minimal systemic absorption and avoids whole-body hormone exposure.

When to Expect Results

• Moisture and comfort may improve in 1–2 weeks

• Full tissue restoration and arousal support typically build over 6–12 weeks

• Ongoing use is often recommended for continued benefit

When to Contact Your Provider

• Reach out to your provider if you experience:

  • Persistent vaginal irritation, itching, or burning

  • Unusual or unpleasant odor or discharge

  • New or worsening pelvic pain

  • Signs of a urinary tract infection (burning, urgency, frequency)

  • Acne, unwanted hair growth, or voice changes

  • No improvement in symptoms after 6–8 weeks of consistent use

  Your care team can adjust your treatment plan, rule out other conditions, or recommend supportive therapies as needed.

Possible Side Effects

DHEA is well tolerated when used vaginally. Rare side effects may include:

• Mild irritation or tingling at the application site

• Occasional increase in discharge or odor (adjust frequency if needed)

• Rare: acne or hair changes if systemically absorbed (uncommon)

❗ Always let your provider know if symptoms persist or worsen.

Frequently Asked Questions

Q: Is this the same as estrogen cream?
A: No—DHEA is a precursor hormone and works more gently. It supports tissue regeneration without direct estrogen exposure.

Q: Will this affect my hormones?
A: Minimal systemic absorption means it usually does not affect hormone levels throughout the body.

Q: Can I use this with arousal cream or other treatments?
A: Yes! It pairs well with arousal creams, oxytocin ODT, and other sexual health supports.

Renew & Reclaim is a compounded prescription medication. It should only be used under the guidance of a licensed provider. While DHEA is widely used off-label in women’s health, safety and effectiveness are closely monitored through personalized care.

Medical Oversight Disclaimer

Optional Add-On Tools

Ask about combining your treatment with:

Arousal Creams

For enhanced touch sensitivity

Supplements

Adjunct to enhanse prescription treatments.

HIV prevention is for everyone who requires it. Women of all orientations are eligible.

PrEP

Contact Us

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